So I have encountered a problem that I have yet to find a solution for. This is why I have come here. Hours of research on the web and I cannot find anything. Anyways, here goes… SYSTEM SPECS: OS- WIN10 64bit-(2019) CPU- I9-9900K-(2019) GPU- EVGA NVIDIA GTX1080 SC-(2017) MOBO- MSI Z390 GAMING PRO CARBON-(2019) RAM- CORSAIR VENGEANCE LPX 3200mhz (16X2)32 - (2019) PSU- EVGA SUPERNOVA 100W G2 GOLD-(2013) CPU COOLING- EVGA CLC 280-(2018) HDD’S; Original drives SAMSUNG 850 EVO 250GB (BOOT)-(2014) SAMSUNG 860 EVO 1TB (GAME LIBRARY) (DEAD)-(2018) SAMSUNG 970 EVO 1TB M.2 (GAME LIBRARY)-(2019) SEAGATE 4TB SSHD SATA (DEAD)-(2014) SEAGATE 2 TB SSHD SATA (DEAD)-(2013) New drives SEAGATE FIRE CUDA SSHD 2TB 7200RPM (DEAD)-(2019) SEAGATE BARRACUDA 4TB 5400RPM (DEAD)-(2019) Items listed dead will not “power on”. I’ve now used 6 workstations/desktops. The issue. About 2 weeks ago I noticed that my original 2 TB SSHD wasn’t loaded in the “my computer” location. I opened my case and verified that all my connections were nice and snug. Everything checked out. I booted and checked again. SSHD was still not showing up. I powered down the system and switched the cables from a different drive and the one that I was looking for showed up. Only problem was that now the other disk I switched cables with disappeared. I did the old switch a roo again and boom! I only showed my boot disk, optical disk, and my m.2. The 4tb 2tb and 1tb SSD didn’t show up in disk manager or bios. Bios stating for respective ports, SATA “Not present”. Trouble shooting with different cables I could not get those drives to come back at all. I called MSI and they mentioned a population rule with SATA while using an M.2 slot. I verified where my M.2 was. I can utilize all 6 SATA ports. MSI had me flash the Bios. Still nothing. Then finally said we need to RMA the board for possible SATA controller failure. I explained to them that my boot drive will still boot normally in every single port. That weekend I pulled out the board to get it ready to ship and threw my old board and CPU in so I had something in the meantime. (MSI g45 z87 gaming, I5-4670k) when I booted the computer up those same drives did not show up. So now I’m thinking, well at least it’s not the MOBO. Feeling worried I ran all 3 drives to best buy and they said they couldn’t get them to power on. So, I bought 2 new SSHD’s on Newegg and talked to Samsung about RMA on my SSD. I received my 2 new SSHD’s (Seagate) today (march 23 2019) and plugged them in. booted up the computer and nothing again. They don’t show up in bios or disk manager. My 250 GB boot drive is on the same SATA pigtail for power and will boot to windows with no issue in any SATA port I put it into on the MOBO. M.2 has remained stable as well. So after I couldn’t get these 2 brand new drives to load I went to my cousin’s house to see if they would power on with his equipment. Nothing with SATA or a hot swap bay. Something in my system is killing my hard drives. And I can’t, for the life of me figure it out. Somehow through all of this my boot drive and M.2 are surviving. So for all the testing I do for getting this figured out is going to require me to sacrifice a hard drive every time I boot until I figure it out? Anyone ever hear or experience anything like this? I have a new PSU and a similar inexpensive HDD coming in 3/26/19 to see if maybe my PSU is the culprit. though my voltages seem to be in operating range. any help or tips appreciated!