It will run, but not super smoothly. I ran Alyx on a GTX 970 using a Valve Index with minimum graphics settings and it had slow downs that made me put it off until a GPU upgrade. The 1660 Ti is about 1.47x as fast, however, the Oculus Quest 2 has about 1.52x the resolution so I'd say it will run about the same. The interactivity is amazing though and I'm looking forward to playing it all the way through. If you're not going to upgrade immediately, the simply styled games (like Beat Saber or Superhot VR) run well.